Holly Middlekauff, M.D.

Associate Professor, Department of Medicine - Division of Cardiology, at the David Geffen School of Medicine, UCLA
 

Contact Information

Division of Cardiology
UCLA Department of Medicine
Box 951679
Los Angeles, CA 90095-1679
On-campus mail: 47-123 CHS 167917
Fax: (310) 206-9133
E-mail: hmiddlekauff@mednet.ucla.edu


Biosketch

 

Dr. Middlekauff graduated from Yale University in 1982 with a B.S. in Biochemistry and received her M.D. from USC School of Medicine in 1986. She continued her training at the UCLA Center for Health Sciences in Internal Medicine and Cardiology and served as Chief Resident in Medicine. In 1992, she joined the UCLA Department of Medicine faculty in the Division of Cardiology. One of her research interests is the effect of acupuncture on the sympathetic nervous system (nerves that carry adrenaline) in patients with heart failure. Heart failure patients with overactivity of the sympathetic nerves are at increased risk of dying. Pharmacological therapies targeted at interrupting this sympathetic activation have been shown to improve survival in patients with heart failure. Acupuncture may provide a complementary means of curbing this sympathetic nerve overactivity in heart failure.

 

Selected References

Middlekauff HR, Yu JL, Hui K. Acupuncture modulates reflex responses to mental stress in humans. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2001; 280:R1462-68.

Shuxia C, Shihong B, Peilun C, et al. Preliminary investigation on the effect of acupuncture of Neiguan (P.6) and Shaofu (H.8) on cardiac function of idiopathic cardiomyopathy. Journal of Traditional Chinese Medicine. 1983; 3:113-120.

Dingjiu H. Effect of acupuncture on left ventricular size and function assessed by echocardiography in patients with stable dilated cardiomyopathy. Journal of Traditional Chinese Medicine. 1985; 5:243-245.