Mark Mandelkern, M.D. Ph.D.

Professor of Physics and Radiological Sciences, UC Irvine; Chief, Positron Emission Tomography, VA Greater Los Angeles Heathcare System; Medical Director, Research Imaging Center, UC Irvine
 

Contact Information

Physics Department, UC Irvine
Irvine, CA 92697
Tel: (949) 824-6944
Fax:
E-mail: markm@uci.edu

Nuclear Medicine Section (115)
VA Greater LA Healthcare System
Los Angeles, CA 90095-1691
Tel: (310) 268-4401
Fax:

Biosketch

 

Dr. Mandelkern has directed the VAGLA PET Center since its founding. He is active in clinical practice and biomedical-imaging research at VAGLAHS, and in imaging, basic physics and statistics research at UC Irvine.

Research: Dr. Mandelkern's human-study research includes PET/MRI and EEG studies of normal brain function, substance abuse, visceral and somatic pain syndromes, epilepsy, dementias, cancer and peripheral perfusion. He works on methods for small-animal autoradiography. His non-biomedical research is in experimental elementary particle physics and statistical interval estimation.
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Selected References

Complementary Hemispheric Specialization for Word and Accent Identification, Berman SM, et al., Neuroimage 19:319-331, 2003.

Regional Cerebral Dysfunction Associated with Mood Disturbances in Abstinent Methamphetamine Abusers, London ED, et al., Archives of General Psychiatry, in press, 2003.

Differences in Regional Gray Matter Volume between Smokers and Non-smokers, Brody AL, et al., Biological Psychiatry, in press, 2003.

A Model for Frequency Dependence of Conductivities of the Live Human Skull, Akhtari M et al., Brain Topogr. 16:39-55, 2003.

Smoking-Induced Ventral Striatal Dopamine Release, Brody AL et al., American Journal of Psychiatry, in press, 2003.

Positron Emission Tomography in Cancer Research and Treatment, Mandelkern MA and Raines J, Technology in Cancer Research and Treatment, 1:423-439, 2002.

Delusional Thoughts and Regional Frontal/Temporal Cortex Metabolism in Alzheimer's Disease, Sultzer DL et al., Am. Journal of Psychiatry 160:341, 2003.

Brain Responses to Visceral and Somatic Stimuli in Patients with Irritable Bowel Syndrome With and Without Fibromyalgia, Chang L, et al., Am. Journal of Gastroenterology 98:1354-61,2003.

Observation of Atomic Antihydrogen, Blanford G et al, Phys.Rev. Lett. 80:3037-40, 1998.

Setting Confidence Intervals for Bounded Parameters, Mandelkern M. Statistical Science 17:149-172, 2002.