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Philip
M. Hanno, M.D. Assistant Clinical Professor, Departments of Urology and Surgery, Univerisity of Pennsylvania, Philadelphia |
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Contact Information Departments
of Urology and Surgery
Philip Hanno, MD has a long-standing interest in interstitial cystitis and has worked with Dr. Alan Wein in this condition and in other areas fro over 25 years. His initial basic science fellowship in the Harrsion Department of Surgical Research at Penn involved urinary tract infection and studies of the glycosaminoglycan (GAG) lining of the bladder. He was the first to demonstrate the protective effects of an exogenous GAG - heparin - when applied in micro amounts to the mucin deficient rabbit bladder (Hanno, Fritz, et al. 1978; Hanno, Parsons et al. 1978). He was involved in the Interstitial Cystitis Association (ICA) in its formative years and has been a Co-Chair of its Medical Advisory Board for the last 15 years. In 1986 he organized the first IC international meeting of experts in Boston. In 1987 he and Dr. Wein organized the first international NIH Conference on Interstitial Cystitis in Bethesda Maryland. These meetings formed the bassis for the first modern era book on IC (Hanno, Staskin et al. 1990). In 1985 and 1986 he received grants from the ICA to study the hormonal relationships of IC and immunohistology of IC. He received merit review grants continuously between 1982 and 1990 from the Veterans' Administration to study factors affecting bacterial adhesion to lower urinary tract mucosa. In 1987 he received an NIH grant for human and animal studies on interstitial cystitis. In 1991 he received NIH funding as a Co-Principal Investigator to study antibacterial defense factors of urinary bladder mucosa. Along with Dr. Wein, Dr. Hanno was an instrumental part of the NIADDK group that in 1987 and 1988 formed what have come to be accepted as the "research criteria" for IC. More recently,
Dr. Hanno has served as Professor and Chairman of the Department
of Urology at Temple University, and then was a medical officer
at the Food and Drug Administration before returning to Penn and
the Division of Urology in 19999. He has written and spoken extensively
on interstitial cystitis, editing a Urologic Clinics of North America
(Hanno 1994) devoted to the subject as well as writing the chapter
on IC for the last two editions of Campbell's Urology textbook (Hanno
1998; Hanno 2002). He co-chaired the interstitial cystitis group
of the Bladder Progress Research Review Group of NIDDK and participated
in the August 2002 report, "Overcoming Bladder Disease"
issued by NIH. He presently maintains a busy clinical practice specializing
in voiding dysfunction, IC and pelvic pain.
Selected References Pontari MA, Hanno PM and Ruggieri MR: Comparison of bladder blood flow in patients with and without interstitial cystitis. J Urol. 162(2);330-334, Aug 1999. Sant GR and Hanno PM: Interstitial cystitis: current issues and controversies in diagnosis. Urology 57(6 Suppl 1);82-88, June 2001. Wein AJ and Hanno PM: Targets for therapy fo the painful bladder. Urology 59(5 Suppl 1);68-73, May 2002.
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